Preheat oven to 425°. Butter and flour 10 of the cups of a standard 12-cup muffin pan, including the area around the cups.
Prepare the crumble topping: In a small bowl mix together 95 grams (⅔ cup) flour, brown sugar, cinnamon, and a pinch of salt. Add melted butter and stir until a crumbly mixture forms. Set aside.
In a medium mixing bowl combine 142 grams (1 cup) flour, 100 grams (½ cup) sugar, 3 grams (½ tsp) salt, baking powder, and baking soda. Whisk to fully combine.
In a large bowl or the bowl of a stand mixer, beat together squash, sourdough discard, oil, eggs, and vanilla extract until evenly combined.
Add dry ingredient mixture to wet ingredient mixture. Mix with a rubber spatula or wooden spoon until ingredients are just evenly incorporated, avoid over-mixing (batter will be lumpy).
Divide batter into the 10 buttered muffin cups, filling the cups full or nearly full. Top each generously with crumble topping (there should be no leftover topping).
Bake 5 minutes then reduce heat to 350° and bake another 15-20 minutes, or until a toothpick inserted in the middle of a center muffin comes out with a few moist crumbs. Allow to cool in pan for 10 minutes, then remove to a wire rack to cool completely.